Urinary excretion of porphyrin precursors and coproporphyrin in healthy females on oral contraceptives.
نویسندگان
چکیده
منابع مشابه
Long-standing changes in the urinary profile of porphyrin isomers after clinical remission of porphyria cutanea tarda.
Patients with overt porphyria cutanea tarda (PCT) show a distinctive and abnormal urinary profile of porphyrin excretion. It is not known, however, whether clinical remission of the disease produces complete normalization of this profile. We selected 46 patients, previously diagnosed with PCT, who after treatment presented normal levels of total porphyrins in urine (< 35 nmol/mmol creatinine). ...
متن کاملUrinary porphyrins and porphyrin precursors in normal pregnancy. Relationship to urinary total oestrogen excretion,.
The relationship between urinary excretion of porphyrins, porphyrin precursors and total oestrogens in normal pregnancy was investigated. Significant increases in total oestrogen, delta-aminolaevulinic acid (ALA) and coproporphyrin (COPRO) excretion were noted. However, no close correlation was found between total oestrogen excretion and urinary output of ALA and COPRO. The results suggest that...
متن کاملEvaluation of urinary porphyrin excretion in neonates born to mothers exposed to airborne hexachlorobenzene.
The existence of a link between hexachlorobenzene (HCB) and porphyria cutanea tarda has been known for a long time. However, the epidemiologic data on effects on health caused by prenatal exposure have not provided convincing evidence that HCB alters porphyrin metabolism. Our objectives were to analyze urinary porphyrin excretion and HCB in maternal serum and fetal cord blood in neonates born i...
متن کاملThe Urinary/fecal Coproporphyrin Ratio in Liver Disease.
In addition to the bile pigments, there are present in the urine and stool another series of pyrrole pigments, the porphyrins. Hemoglobin, myoglobin, and other respiratory pigments contain as their prosthetic group a porphyrin of Type III configuration. The porphyrin excreted in urine and feces by normal individuals, and in most pathological states, is coproporphyrin Type I. This substance cann...
متن کاملUrinary porphyrin excretion in hepatitis C infection.
A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism. Moreover, there is evidence of a role of porphyrinopathies in hepatocarcinogenesis. The aim of our study was to obtain data on the prevalence and patterns of heme metabolism alterations in patients with chronic hepa...
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ورودعنوان ژورنال:
- British medical journal
دوره 1 5488 شماره
صفحات -
تاریخ انتشار 1966